Decoding how the human proteasome recognizes branched ubiquitin chains. Draczkowski P, Chen SN, Chen T, Wang YS, Shih HA, Huang JYC, Tsai MC, Lin SY, Lin S, Viner R, Chang YC, Wu KP & Hsu STD. Researchers at National Taiwan University have uncovered, for the first time at atomic resolution, how the human proteasome recognizes branched ubiquitin chains. This breakthrough reveals... Read more

Dendritic cell-targeted liposomes for cancer immunotherapy via inhibition of aryl hydrocarbon receptor.

Zhang CG, Yeh CY, Hsu SY, Prakash M, Abarientos AB, Chiang-Hsieh HM, Lin YY, Ortiz CLD, Yang LW, Liang PH, Wu HC, Lee YL. Journal of Nanobiotechnology (2025)

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Structural basis of K11/K48-branched ubiquitin chain recognition by the human 26S proteasome.

Draczkowski P, Chen SN, Chen T, Wang YS, Shih HA, Huang JYC, Tsai MC, Lin SY, Lin S, Viner R, Chang YC, Wu KP & Hsu STD. Nature Communications (2025) Video

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Structural basis of enhanced stalling efficiency of an engineered ribosome arrest peptide.

Sriramoju MK, Ko TP, Draczkowski P, Hsu STD. Nucleic Acids Research (2025)

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