突破重組豆科凝集素活化瓶頸　揭示改變聚醣辨識的關鍵機制 Liu YM, Nguyen HTV, Chen X, Mahmud SA Md, ChenTH, Liao KS, Lo JM, Kan TC, Ren CT, Ma C. 豆科凝集素是豆科植物產生的一種蛋白質，專門與各種聚醣分子結合，扮演廣效病毒防禦或訊號傳遞的角色。然而，要深入研究其特質，必須取得具有活性的重組蛋白，這是科學界長久以來所面臨的難題。..更多

BMAL1–HIF2A heterodimer modulates circadian variations of myocardial injury. Ruan W*, Li T, Bang IH, Lee J, Deng W,...Tsai KL*, Eltzschig HK*. Acute myocardial infarction is a leading cause of morbidity and mortality worldwide. Clinical studies have shown that the severity of cardiac injury after myocardial infarction exhibits a circadian pattern, with larger infarcts and poorer outcomes in patients experiencing morning-onset events. However, the molecular mechanisms underlying these diurnal variations remain unclear..更多

Pentameric Architecture of the SARS-CoV-2 Envelope Protein Revealed by SEC-MALS, Cryo-EM, and Molecular Dynamics.

Weng ZW, Farhat D, Lee JY, Hsu STD. The Journal of Physical Chemistry B (2026)

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Altering the carbohydrate-binding specificity of the legume lectin FRIL through structure-guided engineering.

Liu YM, Nguyen HTV, Chen X, Mahmud SA Md, ChenTH, Liao KS, Lo JM, Kan TC, Ren CT, Ma C. Nature Communications/b> (2026)

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Mechanistic Insights into Unary Peptide–Membrane Interactions Enable Stable Encapsulation and Trigger-Responsive Peptidyl Liposomes.

Gao HD, Hong JL, Jian CB, Chen TH, Chang NC, Meeroekyai S, He RY, Liao YT, Wang CH, Su CJ, Jeng US, Ho MC, Chen YJ, Lee HM. Journal of the American Chemical Society (2026)

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