Visualization of the first contact between the earliest reported human coronavirus and its human receptor molecule Tsai, YX, Chien YC, Hsu MF, Khoo KY, Hsu ST Coronavirus 229E is the earliest reported human coronavirus (hCoV-229E). Here, the authors used cryo-EM, glycoproteomics, and modeling to generate... Read more

Real-space heterogeneous reconstruction, refinement, and disentanglement of CryoEM conformational states with HetSIREN.

Herreros D, Mata CP, Noddings C, Irene D, Krieger J, Agard DA, Tsai MD, Sorzano COS, Carazo JM. Nature Communications (2025)

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Impacts of D-aspartate on the Aggregation Kinetics and Structural Polymorphism of Amyloid β Peptide 1–42.

Hsiao LC, Lee CH, Mazmanian K, Yoshida M, Ito G, Murata T, Utsunomiya-Tate N, Haino T, Tate SI, Hsu STD. Journal of Molecular Biology (2025)

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Changes of the lipid membrane structures caused by chain-length-dependent doxorubicin embedment in PEGylated liposomes.

Kang JJ, Huang ZC, Tang LW, Su CJ, Gao HD, Lee HM, Jeng US. Journal of Applied Crystallography (2025)

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